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J Clin Pathol doi:10.1136/jcp.2008.060863

NON MELANOCYTIC MIMICS OF MELANOMA Part-I: INTRAEPIDERMAL MIMICS

  1. Zaid Kamal Saeed Kamil (dr_zaidkamil{at}yahoo.com)
  1. University Health Network, Canada
    1. Bonnie Tong (bonnie.tong{at}utoronto.ca)
    1. Banting Institute, Canada
      1. Ayman Al Habeeb (ayman.alhabeeb{at}uhn.on.ca)
      1. University Health Network, Canada
        1. Danny Ghazarian (danny.ghazarian{at}uhn.on.ca)
        1. University Health Network, Canada
          • Published Online First 17 October 2008

          Abstract

          Melanoma comprises a wide range of cytological and architectural features histopathologically and hence can mimic many benign and malignant lesions of epithelial, mesenchymal and hematopoietic cell lines of differentiation. Therefore, analysis and close clinical, histologic, histochemical and immunohistochemical correlation is vital in distinguishing challenging melanoma cases from their mimics. In this review, we emphasize the different features of the benign, pre-malignant and malignant intraepidermal non-melanocytic tumors and tumor-like lesions that can closely mimic intraepidermal melanoma (melanoma in-situ).

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