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J Clin Pathol doi:10.1136/jcp.2007.053108

Brucellosis in United Kingdom – a risk to laboratory workers? Recommendations for prevention and management of laboratory exposure

  1. Srinivasulu Reddy (srinivasulu.reddy{at}bartsandthelondon.nhs.uk)
  1. Barts and The London NHS Trust, United Kingdom
    1. Rohini Manuel (rohini.manuel{at}bartsandthelondon.nhs.uk)
    1. Barts and The London NHS Trust, United Kingdom
      1. Elizabeth Sheridan (liz.sheridan{at}bartsandthelondon.nhs.uk)
      1. Barts and The London NHS Trust, United Kingdom
        1. Garry Sadler (garry.sadler{at}bartsandthelondon.nhs.uk)
        1. Barts and The London NHS trust, United Kingdom
          1. Sneha Patel (sneha.patel{at}kingstonhospital.nhs.uk)
          1. Kingston Hospitals NHS Trust, United Kingdom
            1. Peter Riley (peter.riley{at}stgeorges.nhs.uk)
            1. St. George’s Healthcare NHS Trust, United Kingdom
              • Published Online First 21 May 2008

              Abstract

              Brucella spp. is an uncommon class 3 pathogen isolated in laboratories serving nonendemic areas. We report four recent cases of brucellosis diagnosed at five different London laboratories which highlights the need to maintain a high index of suspicion for brucellosis in patients with a history of travel to and/or consumption of unpasteurised foods from endemic areas. We propose a protocol for risk categorisation, and describe the strategy adopted for serological follow-up of exposed staff and use of postexposure prophylaxis.

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