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J Clin Pathol doi:10.1136/jcp.2007.054312

Neurologically presenting Whipple’s Disease – a Case Report and Review of the Literature

  1. Michael J Buckle (bucklemj{at}cardiff.ac.uk)
  1. Cardiff University, United Kingdom
    1. Richard W Ellis (richard.ellis{at}stft.nhs.uk)
    1. South Tyneside NHS Foundation Trust, United Kingdom
      1. Michael Bone (michael.bone{at}stft.nhs.uk)
      1. South Tyneside NHS Foundation Trust, United Kingdom
        1. Hilmi Lockman (hilmi.lockman{at}stft.nhs.uk)
        1. South Tyneside NHS Foundation Trust, United Kingdom
          • Published Online First 1 April 2008

          Abstract

          A previously healthy male with subacute onset right leg weakness is suspected to have an astrocytoma after a lesion is demonstrated via imaging. However a subsequent biopsy demonstrated the presence of foamy macrophages containing periodic acid-Schiff staining granules, suggesting Whipple’s disease as a possible diagnosis. We here present the case and the report on the patient’s current clinical status.

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