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J Clin Pathol 65:473 doi:10.1136/jclinpath-2011-200527
  • PostScript
  • Letter to the Editor

Detection of Y chromosomal material in ovarian (gonadal) tumours

  1. Colin J R Stewart
  1. Correspondence to Dr Colin J R Stewart, Department of Histopathology, King Edward Memorial Hospital, Bagot Road, Subiaco, Perth, WA 6008, Australia; colin.stewart{at}health.wa.gov.au

  1. Contributors CJRS is the sole contributor.

  • Accepted 1 November 2011
  • Published Online First 29 November 2011

I read the article by Shahsiah and colleagues with interest.1 The authors analysed 47 ovarian germ cell tumours for the presence of testis-specific protein Y-encoded (TSPY) using a PCR technique and identified significant levels of TSPY in seven cases. The importance of identifying Y chromosomal material in these cases, and in phenotypic women generally, is that such patients have increased risk of …

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