Detection of Y chromosomal material in ovarian (gonadal) tumours
- Correspondence to Dr Colin J R Stewart, Department of Histopathology, King Edward Memorial Hospital, Bagot Road, Subiaco, Perth, WA 6008, Australia;
Contributors CJRS is the sole contributor.
- Accepted 1 November 2011
- Published Online First 29 November 2011
I read the article by Shahsiah and colleagues with interest.1 The authors analysed 47 ovarian germ cell tumours for the presence of testis-specific protein Y-encoded (TSPY) using a PCR technique and identified significant levels of TSPY in seven cases. The importance of identifying Y chromosomal material in these cases, and in phenotypic women generally, is that such patients have increased risk of …