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J Clin Pathol 62:350-356 doi:10.1136/jcp.2008.062646
  • Original articles

Age-dependent penetrance of different germline mutations in the BRCA1 gene

Table 9 Cox regression analysis between specific BRCA1 exon mutation and age at diagnosis limited to breast cancer only
Mutation Hazard ratio p Value (95% CI)
Exon 11 0.61 0.1 (0.32 to 1.13)
Exon 2 0.26 0.002 (0.11 to 0.62)
Exon 13 0.80 0.6 (0.32 to 2.03)

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