rss
J Clin Pathol 2009;62:345-349 doi:10.1136/jcp.2008.058537
  • Original article

A review of eGFR reporting after 6 months in practice

  1. A Kremmyda,
  2. W D Neithercut
  1. Department of Clinical Biochemistry, Wirral University Teaching Hospital NHS Foundation Trust, Arrowe Park Hospital, Upton, Wirral, UK
  1. Dr William D Neithercut, Department of Clinical Biochemistry, Wirral University Teaching Hospital NHS Foundation Trust, Arrowe Park Hospital, Upton, Wirral CH49 5PE, UK; duncan.neithercut{at}whnt.nhs.uk
  • Accepted 23 August 2008

Abstract

Background: Following the introduction of routine calculation of estimated glomerular filtration rate (eGFR) from all serum creatinine values in samples received from general practice it was noted that there was a preponderance of values consistent with chronic kidney disease (CKD) stage 3 or higher.

Methods: A review was conducted of all eGFR values from 51 314 individuals received from primary care during October 2006 to April 2007.

Results: It was found that more than 25% of eGFR results indicated CKD stage 3 or higher. The median age in this group was 64 years (range 18–104 years) while that of the local general population according to the 2001 census was 40 years (range 18–104 years); these ages were statistically significantly different (p<0.001). There was no difference between the groups with regard to gender. The eGFR data were therefore corrected for age distribution, and an estimated prevalence of 5.6% of eGFR consistent with CKD stage 3 was found. This was a higher proportion than estimates of CKD suggested before the introduction of eGFR.

Conclusions: The higher proportion of CKD stage 3 may be due to difference in age and gender in populations studied, as there is a marked effect of age on calculated eGFR values found.

Footnotes

  • Competing interests: None.

Register for free content

The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.