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J Clin Pathol 2009;62:1051 doi:10.1136/jcp.2009.069591
  • PostScript
  • Letter to the Editor

Receiver-operating characteristic curve analysis in diagnostic, prognostic and predictive biomarker research: trade-off between sensitivity and specificity with change of test cut-offs

  1. Bhavneet Bharti1,
  2. Sahul Bharti2
  1. 1
    Health Education Division, Department of Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
  2. 2
    Build Healthy India Movement (BHIM), Khuda Ali Sher, UT Chandigarh, India
  1. Correspondence to Dr Bhavneet Bharti, Health Education Division, Department of Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, PIN-160012, India; bhavneetb{at}yahoo.com
  • Accepted 1 July 2009

We read with keen interest the Leading article by Kjetil Søreide entitled “Receiver-operating characteristic curve analysis in diagnostic, prognostic and predictive biomarker research.”1 We, indeed, congratulate the author for providing very useful information to the readers, yet there is one glaring error in fig 1B provided …

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