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J Clin Pathol 61:689-696 doi:10.1136/jcp.2006.041830
  • Demystified

Immunohistochemical markers as predictive tools for breast cancer

Table 3 Markers and their value in prediction in breast cancer
Established and in routine clinical use Potential for clinical use; need refinement of scoring systems or antibodies Research interest, less likely to be used clinically
Oestrogen receptor Epidermal growth factor receptor P53
Progesterone receptor Ki-67 (MIB-1) Cyclin E, cyclin D1, p21, p27
HER2 Topoisomerase II alpha Bcl2, bax, bcl-x, survivin

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