Gallbladder adenocarcinoma: first report in a patient with AIDS
- N Mourra1,
- M-G Lebrette2,
- C Hoeffel3,
- F Paye4
- 1Department of Pathology, Hôpital St-Antoine, Paris, France
- 2Department of Radiology, Hôpital St-Antoine, Paris, France
- 3Department of Infectious Diseases, Hôpital Tenon, Paris, France
- 4Department of Surgery, Hôpital St-Antoine, Paris, France
- Dr Najat Mourra, Department of Pathology, Hôpital St-Antoine, 184, rue du faubourg St-Antoine, 75012, Paris, France; najat.mourra{at}sat.ap-hop-paris.fr
- Accepted 2 March 2007
Although a wide spectrum of AIDS-related cholangiopathy has been reported periodically, malignant tumours, commonly seen in patients with AIDS, are very rare in the gallbladder, with only handful of reports in the literature: Kaposi’s sarcoma, and malignant lymphoma.1 2 We describe the first case of gallbladder adenocarcinoma in a patient with AIDS.
A 36-year-old man, HIV seropositive at 24, without familial history of gallbladder carcinoma, was hospitalised with right upper quadrant abdominal pain. He had chronic liver disease, hepatitis B virus-related, but no previous diagnosis of an HIV-related opportunistic infection. He was on highly active antiretroviral therapy (HAART); 2 years previously he had developed intestinal malignant non-Hodgkin lymphoma, treated by surgery and chemotherapy. The CD4+ lymphocyte count was 30/mm …
