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J Clin Pathol 60:740-748 doi:10.1136/jcp.2006.044719
  • Review

Best practice in primary care pathology: review 8

Table 5

 Simple dose reduction scheme for management of over-anticoagulation

INR % dose reduction Number (days) of omitted doses
Derived from Baglin.41
Target INR 2.5
3.0–3.5 15 0
3.6–4.0 20 0
4.1–5.0 25 0
5.1–6.0 25 0
6.1–7.9 33 2
>8.0 50 3
Target INR 3.5
4.1–5.0 15 0
5.1–6.0 20 0
6.1–7.9 33 2
>8.0 50 3

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