Best practice in primary care pathology: review 7
- W S A Smellie1,
- J Forth2,
- S R S Smart3,
- M J Galloway4,
- W Irving5,
- D Bareford6,
- P O Collinson7,
- K G Kerr8,
- G Summerfield9,
- P J Carey10,
- Rubin Minhas11
- 1Department of Chemical Pathology, Bishop Auckland General Hospital, Cockton Hill Road, Bishop Auckland, County Durham, UK
- 2Sowerby Centre for Health Informatics, Bede House, All Saints Business Centre, Newcastle upon Tyne, UK
- 3PRODIGY Sowerby Centre for Health Informatics at Newcastle, Bede House, All Saints Business Centre, Newcastle upon Tyne, UK
- 4Department of Haematology, City Hospitals Sunderland NHS Foundation Trust, Sunderland Royal Hospital, Kayll Road, Sunderland, UK
- 5Department of Microbiology, School of Molecular Medical Sciences, University Hospital, Queen’s Medical Centre, Nottingham, UK
- 6Department of Haematology, Russells Hall Hospital, Dudley, West Midlands, UK
- 7Department of Chemical Pathology, Jenner Wing, St George’s Hospital, London, UK
- 8Department of Microbiology, Harrogate District Hospital, Harrogate, North Yorkshire, UK
- 9Department of Haematology, Queen Elizabeth Hospital, Gateshead, UK
- 10Department of Haematology, Royal Victoria Infirmary, Newcastle upon Tyne, UK
- 11Medway PCT Unit 2, Ambley Green, Bailey Drive, Gillingham Business Park, Kent, UK
- Correspondence to: Dr W S A Smellie Department of Chemical Pathology, Bishop Auckland General Hospital, Cockton Hill Road, Bishop Auckland County, Durham DL14 6AD, UK; info{at}smellie.com
- Accepted 2 October 2006
- Published Online First 17 October 2006
Abstract
This seventh best-practice review examines four series of common primary care questions in laboratory medicine: (1) blood count abnormalities 2; (2) cardiac troponins; (3) high-density lipoprotein cholesterol; and (4) viral diseases 2. The review is presented in a question–answer format, with authorship attributed for each question series. The recommendations are a précis of guidance found using a standardised literature search of national and international guidance notes, consensus statements, health policy documents and evidence-based medicine reviews, supplemented by Medline Embase searches to identify relevant primary research documents. The recommendations are not standards, but form a guide to be set in the clinical context. Most are consensus based rather than evidence based. They will be updated periodically to take account of new information.
- ACS, acute coronary syndrome
- CHD, coronary heart disease
- CLL, chronic lymphocytic leukaemia
- CMV, cytomegalovirus
- EBV, Epstein–Barr virus
- FBC, full blood count
- GMS, General Medical Services
- HDL-C, high-density lipoprotein cholesterol
- LDL-C, low-density lipoprotein cholesterol
Footnotes
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* These organisations contributed direct funding to support the project start-up.
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Published Online First 17 October 2006
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This work has been supported (in alphabetical order) by the Association of Clinical Biochemists*, Association of Clinical Pathologists*, Association of Medical Microbiologists, British Society for Haematology, Royal College of General Practitioners, Royal College of Pathologists* and the Sowerby Centre for Health Informatics in Newcastle, representatives of whom have contributed to the reviewing process. The opinions stated are, however, those of the authors.








