Primary cardiac post-transplantation lymphoproliferative disorder—T cell type: a case report and review of the literature
- 1Department of Histopathology, Postgraduate Institute of Medical Education & Research, Chandigarh, India
- 2Department of Nephrology, Postgraduate Institute of Medical Education & Research, Chandigarh, India
- 3Department of Histopathology, Postgraduate Institute of Medical Education & Research, Chandigarh, India
- Correspondence to:
Dr K Joshi
Deptartment of Histopathology, Postgraduate Institute of Medical Education & Research, Chandigarh 160012, India; kus_joshi{at}yahoo.com
- Accepted 6 July 2006
Post-transplantation lymphoproliferative disorder (PTLD) has been recognised as a significant complication affecting 2% of all organ allograft recipients.1 The incidence of PTLD has increased in recent years because of the steady increase in the number of organs transplanted.1 The early diagnosis of PTLD is complicated by its wide spectrum of clinical presentations and the difficulty in distinguishing it from other more frequent complications—allograft rejection and opportunistic infection.
Case report
A 20-year-old man presented with fever, headache and cough. He was a recipient of live-related renal allograft 7 years previously, at which time he started receiving standard immunosuppressive treatment. He was found to be positive for hepatitis B s antigen and e antigen. Other systemic examinations were normal.
Laboratory tests revealed bicytopenia. Despite appropriate antibiotic coverage, the patient sustained cardiac arrest.
A complete autopsy was performed after obtaining informed consent. A …
