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J Clin Pathol 2007;60:1195-1204 doi:10.1136/jcp.2007.048512
  • Review

Best practice in primary care pathology: review 10

  1. W S A Smellie1,
  2. N Shaw2,
  3. R Bowley2,
  4. M F Stewart3,
  5. A M Kelly4,
  6. P J Twomey5,
  7. P R Chadwick6,
  8. J B Houghton7,
  9. J P Ng8,
  10. A J McCulloch9
  1. 1
    Department of Chemical Pathology, Bishop Auckland General Hospital, Bishop Auckland, UK
  2. 2
    Sowerby Centre for Health Informatics, Newcastle upon Tyne, UK
  3. 3
    Dept of Clinical Biochemistry, Salford Royal NHS Foundation Trust, Salford, UK
  4. 4
    Department of Chemical Pathology, Wythenshawe Hospital, Manchester, UK
  5. 5
    Department of Chemical Pathology, Ipswich Hospital, Ipswich, UK
  6. 6
    Department of Microbiology, Salford Royal NHS Foundation Trust, Salford, UK
  7. 7
    Department of Haematology, Salford Royal NHS Foundation Trust, Salford, UK
  8. 8
    Department of Haematology, Barnsley Hospital NHS Foundation Trust, Barnsley, UK
  9. 9
    Department of Medicine, Bishop Auckland General Hospital, Bishop Auckland, UK
  1. Dr W S A Smellie, Department of Chemical Pathology, Bishop Auckland General Hospital, Cockton Hill Road, Bishop Auckland, County Durham DL14 6AD, UK; info{at}smellie.com
  • Accepted 24 April 2007
  • Published Online First 11 May 2007

Abstract

This tenth best practice review examines four series of common primary care questions in laboratory medicine: (i) antenatal testing in pregnant women; (ii) estimated glomerular filtration rate calculation; (iii) safety testing for methotrexate; and (iv) blood glucose measurement in diabetes. The review is presented in question–answer format, referenced for each question series. The recommendations represent a précis of guidance found using a standardised literature search of national and international guidance notes, consensus statements, health policy documents and evidence-based medicine reviews, supplemented by Medline Embase searches to identify relevant primary research documents. They are not standards but form a guide to be set in the clinical context. Most are consensus rather than evidence-based. They will be updated periodically to take account of new information.

Footnotes

  • Competing interests: This work has been supported (in alphabetical order) by the Association of Clinical Biochemists*, Association of Clinical Pathologists*, Association of Medical Microbiologists, British Society for Haematology, Royal College of General Practitioners, Royal College of Pathologists* and the Sowerby Centre for Health Informatics in Newcastle (SCHIN), representatives of whom have contributed to the reviewing process. The opinions stated are however those of the authors. *These organisations contributed direct funding to support the project start up.

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