Best practice in primary care pathology: review 3
- W S A Smellie1,
- J Forth2,
- D Bareford3,
- P Twomey4,
- M J Galloway5,
- E C M Logan6,
- S R S Smart7,
- T M Reynolds8,
- C Waine9
- 1Department of Chemical Pathology, Bishop Auckland General Hospital, Bishop Auckland, County Durham, UK
- 2Sowerby Centre for Health Informatics, Bede House, All Saints Business Centre, Newcastle upon Tyne, UK
- 3Department of Haematology, City Hospital, Birmingham, West Midlands, UK
- 4Department of Chemical Pathology, Ipswich Hospital, Heath Road, Ipswich, UK
- 5Department of Haematology, E Floor Haematology Office, Sunderland Royal Hospital, Sunderland, UK
- 6Department of Haematology, Kings Mill Centre, Sutton in Ashfield, Nottingham, UK
- 7PRODIGY, Sowerby Centre for Health Informatics at Newcastle, Bede House, All Saints Business Centre
- 8Department of Clinical Chemistry, Queens Hospital, Burton on Trent, Staffordshire, UK
- 9Department of Primary Care, University of Sunderland, St Georges Way, Sunderland
- Correspondence to: W S A Smellie Department of Chemical Pathology, Bishop Auckland General Hospital, Cockton Hill Road, Bishop Auckland, County Durham DL14 6AD, UK; info{at}smellie.com
- Accepted 3 November 2005
Abstract
This best practice review examines four series of common primary care questions in laboratory medicine: (i) “minor” blood platelet count and haemoglobin abnormalities; (ii) diagnosis and monitoring of anaemia caused by iron deficiency; (iii) secondary hyperlipidaemia and hypertriglyceridaemia; and (iv) glycated haemoglobin and microalbumin use in diabetes. The review is presented in question–answer format, referenced for each question series. The recommendations represent a précis of guidance found using a standardised literature search of national and international guidance notes, consensus statements, health policy documents and evidence-based medicine reviews, supplemented by Medline Embase searches to identify relevant primary research documents. They are not standards, but form a guide to be set in the clinical context. Most of the recommendations are based on consensus rather than evidence. They will be updated periodically to take account of new information.
- ADA, American Diabetes Association
- CVD, cardiovascular disease
- DCCT, Diabetes Control and Complications Trial
- GMS, General Medical Services
- HbA1c, glycated haemoglobin
- LDL, low-density lipoprotein
- MCV, mean cell volume
- NICE, National Institute for Health and Clinical Excellence
Footnotes
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Competing interests: None declared.








