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J Clin Pathol 59:557-563 doi:10.1136/jcp.2005.031112
  • Review

An update on molecular genetics of gastrointestinal stromal tumours

Table 4

 Summary of cytogenetic changes in gastrointestinal stromal tumours

Changes Method Number of cases Reference
CGH, comparative genomic hybridisation; FISH, fluorescent in situ hybridisation.
−1p, −8p, −9, −10p, −10q, −13, −14q, −22q FISH 14 Kim, 200099
−14q, −22q FISH 12 Breiner et al106
−1p, −9p, −14q, −22q, +5p, +8q, +17q, +20q, CGH 95 El-Rifai et al100
−1, −7, −9, −13q14 (Rb1), −14q, −15, −22q, +3, +4, +8, +10 FISH 22 Debiec-Rychter et al104
−1p, −13q, −14, −15, −22, +1q, +5, +17q, +20p FISH 14 Derré et al105
−1p, −14, −21, −22, +7, Cytogenetics, spectral caryotyping 10 Andersson et al35
−1p, −9p, −10q, −13q, −14, −15, −22, +5 Cytogenetics 19 Gunawan, 2002107
−1p, −9q, −14q, −15q, −22q, +4q, +5, +8q CGH 52 Gunawan et al108

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