Frequent molecular abnormalities in head and neck squamous cell carcinoma
| LOH 9p | 70–80% |
| LOH 3p | 60–70% |
| LOH 17p | 50–70% |
| LOH 11q | 30% |
| LOH 13q | 30% |
| Inactivation of p16ink4A (homozygous deletion, promoter methylation, point mutation) | 80% |
| Inactivation of FHIT and RASSF1A p53 mutation | 50–80% |
| Cyclin D1 amplification | 30% |
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Online ISSN 1472-4146
Copyright © 2012 by the BMJ Publishing Group Ltd & Association of Clinical Pathologists. All rights reserved.
