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J Clin Pathol 2006;59:1133-1150 doi:10.1136/jcp.2005.031260
  • My approach

An approach to duodenal biopsies

  1. S Serra,
  2. P A Jani
  1. Department of Pathology, University Health Network and Toronto Medical Laboratories, Toronto, Ontario, Canada
  1. Correspondence to:
    S Serra
    Department of Pathology, University Health Network and Toronto Medical Laboratories, 200 Elizabeth Street, 11th Floor, Toronto, Ontario, M5G 2C4, Canada;stefano.serra{at}uhn.on.ca
  • Accepted 2 February 2006
  • Published Online First 5 May 2006

Abstract

The introduction of endoscopy of the upper digestive tract as a routine diagnostic procedure has increased the number of duodenal biopsy specimens. Consequently, the pathologist is often asked to evaluate them. In this review, a practical approach to the evaluation of a duodenal biopsy specimen is discussed. An overview of the handling of specimens is given and the normal histology and commonly encountered diseases are discussed. Finally, a description of commonly seen infections is provided, together with an algorithmic approach for diagnosis.

Footnotes

  • Published Online First 10 May 2006

  • Competing interests: None declared.

This Article

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    1. jcp.2005.031260v1
    2. jcp.2005.031260v2
    3. 59/11/1133 most recent

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