Table 1
Laboratory and clinical features of the patients
| Patient | Age/Sex | Bleeding symptoms | Associated disorders | Platelet (×109/l) | Bleeding time | Ristocetin | ADP (2μM) | ADP (10µM) | Collagen (2µM) | Epinephrine (10 µM) | ATP release (2 µM ADP) | ATP release (10 µM ADP) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CRF, chronic renal failure; EPO, erythropoietin (chronic anaemia); m, months; N, normal; ND, not done; y, years. | ||||||||||||
| 1 | 7y/M | Present | CRF, EPO responsive anaemia, hepatomegaly | 236 | 19 min | N | Reduced primary aggregation | Minimal improvement | Reduced primary aggregation | Reduced primary aggregation | Absent | Minimal |
| 2 | 1y 6m/M | Absent | None | 406 | 9 min | N | Absent secondary aggregation | N | N | N | ND* | ND* |
| 3 | 1 y/F | Absent | None | 217 | 25 min | N | Absent secondary aggregation | Minimal improvement | N | Reduced secondary aggregation | Absent | Minimal |
| 4 | 3y 6m/M | Absent | None | 510 | 9 min 30 s | N | N | N | N | N | N | N |
| 5 | 2y 6m/M | Absent | None | 232 | 15 min 7 s | N | Absent secondary aggregation | Minimal improvement | N | Absent secondary aggregation | ND | ND |
| 6 | 9y 8m/M | Present | CRF | 257 | 21 min | N | Absent secondary aggregation | ND | N | ND* | ND* | ND* |
| 7 | 5y 9m/M | Absent | None | 300 | 4 min 30 s | N | N | N | N | ND* | ND* | ND* |
