Table 3
Relation between HER-2 gene amplification determined by CISH in histology and CISH in cytology and protein overexpression detected by immunocytochemistry
| CISH in histology | ||||
|---|---|---|---|---|
| No amplification (2–6) | Low amplification (6–10) | High amplification (>10) | Total | |
| CISH, chromogenic in situ hybridisation. | ||||
| Immunocytochemistry | ||||
| Negative (0, 1+) | 72 | 3 | 0 | 75 |
| Indeterminate (2+) | 0 | 6 | 7 | 13 |
| Positive (3+) | 0 | 1 | 5 | 6 |
| Total | 72 | 10 | 12 | 94 |
| CISH in cytology | Totals | |||
| No amplification (2–6) | 72 | 0 | 0 | 72 |
| Low amplification (6–10) | 0 | 11 | 0 | 11 |
| High amplification (>10) | 0 | 1 | 10 | 11 |
| Total | 72 | 12 | 10 | 94 |
