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J Clin Pathol 58:486-489 doi:10.1136/jcp.2004.023291
  • Original article

Analysis of Bcl-2 protein expression in choroidal melanomas

Table 3

 Clinicopathological characteristics of choroidal melanomas with and without Bcl-2 expression

Variable Choroidal melanoma
Bcl-2 positive Bcl-2 negative p Value
HPF, high power fields.
Total 12/24 (50%) 12/24 (50%) 1.00
Mean age (SEM) 56.6 (10.8) 66.9 (14.0) 0.2
Site
    Left eye 6/12 (50%) 7/12 (58%) 0.3
    Right eye 6/12 (50%) 5/12 (42%) 0.2
Cell type
    Mixed cell type 9/12 (75%) 10/12 (83%) 0.2
    Epithelioid cell type 3/12 (25%) 2/12 (16%) 0.2
    Spindle cell type 0/12 (0.0%) 3/12 (25%) 0.0
    Juxtapapillary melanoma 0/12 (0.0%) 2/12 (16%) 0.0
Mitotic figures (/10 HPF) 0.9 (0.1) 0.3 (0.1%) 0.2
    Invasion of long ciliary nerve 0/12 (0.0%) 1/12 (8.0%) 0.00
    Extension through emissary canal 4/12 (33%) 2/12 (16%) 0.00
    Tumour cells in vascular lakes 2/12 (16%) 2/12 (16%) 1.0
    Extraocular extension 0/12 (0.0%) 0/12 (0.0%) 1.0
    Invasion of the sclera 0/12 (0.0%) 1/12(8.0%) 1.0
    Ciliary body involvement 0/12 (0.0%) 1/12 (8.0%) 0.0
    Invasion of the optic nerve 0/12 (11%) 1/12 (8.0%) 0.00

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