Table 1
Time of antibody sampling, sensitivity, specificity, and PPV for predicting PPTD
| Time of sampling | Sensitivity | Specificity | PPV |
|---|---|---|---|
| Sensitivity, specificity, and PPV of thyroid antibody (antimicrosomal and antithyroid peroxidase) in PPTD prediction derived from published studies. Sampling times varied. Early pregnancy: 1st and 2nd trimesters; early postpartum: from delivery to 5 months after delivery; late postpartum: 6 or more months after delivery. Adapted from Premawardhana et al.31 | |||
| PPTV, postpartum thyroid dysfunction; PPV, positive predictive value. | |||
| Early pregnancy | 0.67–1.00 | 0.62–0.93 | 0.31–0.55 |
| 3rd trimester | 0.71 | 0.92 | 0.52 |
| Delivery/early postpartum | 0.45–0.89 | 0.91–0.97 | 0.4–0.73 |
| Late postpartum | 0.46–0.86 | 0.9–0.98 | 0.52–0.78 |
