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J Clin Pathol 58:402-405 doi:10.1136/jcp.2004.022103
  • Original article

High co-prevalence of genogroup 1 TT virus and human papillomavirus is associated with poor clinical outcome of laryngeal carcinoma

Table 2

 Statistical comparison of viral prevalences between the different study groups

Laryngeal papillomatosis (n = 10) Total SCC (n = 25) SCC without tumour progression (n = 14) SCC with tumour progression* (n = 11)
HPV, human papillomavirus; NS, not significant; SCC, squamous cell carcinoma; TTV, transfusion transmitted virus.
HPV prevalence
    Healthy individuals (n = 40) p<0.001 NS NS p = 0.001
    Laryngeal papillomatosis (n = 10) p = 0.005 p<0.001 NS
    SCC without tumour progression (n = 14) p = 0.005
Genogroup 1 TTV prevalence
    Healthy individuals (n = 40) NS p<0.0001 NS p<0.0001
    Laryngeal papillomatosis (n = 10) NS NS p = 0.03
    SCC without tumour progression (n = 14) p = 0.017
Coinfection prevalence
    Healthy individuals (n = 40) NS p = 0.001 NS p<0.0001
    Laryngeal papillomatosis (n = 10) NS NS p = 0.043
    SCC without tumour progression (n = 14) p<0.001

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