Table 3
Chromosomal and gene characteristics according to stage and lymph node status
| Variable | No. cases | T3–4 | p Value | No. cases | Node + | p Value | |
|---|---|---|---|---|---|---|---|
| Significance was assessed using the χ2 test. Those values underlined showed a positive trend when chromosomal and gene characteristics were compared with T3–4 stage and lymph nodal involvement, even though the results were not significant. | |||||||
| *Median value. | |||||||
| NS, not significant. | |||||||
| Monosomy 3 | ⩽18* | 22 | 40.9 | 0.03 | 20 | 35.0 | NS |
| >18* | 20 | 75.0 | 20 | 50.0 | |||
| Polysomy 3 | ⩽18* | 20 | 65.0 | NS | 19 | 42.1 | NS |
| >18* | 22 | 50.0 | 21 | 42.9 | |||
| Aneusomy 3 | ⩽54* | 23 | 60.9 | NS | 22 | 40.9 | NS |
| >54* | 19 | 52.6 | 18 | 44.4 | |||
| Monosomy 7 | ⩽19* | 23 | 43.5 | 0.04 | 22 | 27.3 | NS |
| >19* | 20 | 75.0 | 20 | 55.0 | |||
| Polysomy 7 | ⩽22* | 21 | 61.9 | NS | 21 | 42.9 | NS |
| >22* | 22 | 54.5 | 21 | 38.1 | |||
| Aneusomy 7 | ⩽48* | 22 | 63.6 | NS | 22 | 50.0 | NS |
| >48* | 21 | 52.4 | 20 | 30.0 | |||
| Monosomy 9 | ⩽22* | 23 | 47.8 | NS | 22 | 27.3 | NS |
| >22* | 21 | 66.7 | 20 | 50.0 | |||
| Polysomy 9 | ⩽2* | 22 | 59.1 | NS | 20 | 40.0 | NS |
| >2* | 22 | 54.5 | 22 | 36.4 | |||
| Aneusomy 9 | ⩽38* | 25 | 60.0 | NS | 24 | 41.7 | NS |
| >38* | 19 | 52.6 | 18 | 33.3 | |||
| Monosomy 17 | ⩽18* | 21 | 42.9 | 0.04 | 20 | 30.6 | NS |
| >18* | 23 | 69.6 | 23 | 47.8 | |||
| Polysomy 17 | ⩽12* | 23 | 65.2 | NS | 22 | 45.5 | NS |
| >12* | 21 | 47.6 | 21 | 33.3 | |||
| Aneusomy 17 | ⩽44* | 21 | 61.9 | NS | 20 | 50.0 | NS |
| >44* | 23 | 52.2 | 23 | 30.4 | |||
| RB heterozygous | ⩽26* | 25 | 44.0 | 0.03 | 23 | 26.1 | NS |
| >26* | 23 | 73.9 | 23 | 52.2 | |||
| 9p21 heterozygous | ⩽24* | 21 | 47.6 | NS | 19 | 36.8 | NS |
| >24* | 19 | 63.2 | 19 | 36.8 | |||
| p53 heterozygous | ⩽28* | 21 | 57.1 | NS | 21 | 33.3 | NS |
| >28* | 18 | 61.9 | 16 | 56.3 | |||
| RB homozygous | No | 27 | 66.7 | NS | 26 | 38.5 | NS |
| Yes | 21 | 47.6 | 20 | 40.0 | |||
| 9p21 homozygous | No | 11 | 36.4 | NS | 11 | 27.3 | NS |
| Yes | 29 | 62.1 | 27 | 40.7 | |||
| p53 homozygous | No | 25 | 56.0 | NS | 25 | 44.0 | NS |
| Yes | 14 | 64.3 | 12 | 41.7 | |||
| HER-2 | <2 | 36 | 556 | NS | 35 | 40.0 | NS |
| >2 | 7 | 51.7 | 7 | 28.6 | |||
