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J Clin Pathol 58:301-307 doi:10.1136/jcp.2004.022830
  • Original article

Clostridium bacteraemia characterised by 16S ribosomal RNA gene sequencing

Table 6

 Comparison of characteristics of patients with clinically relevant clostridium bacteraemia and those with clostridium pseudobacteraemia

Characteristics Number of patients (%) p Value
Clinically relevant bacteraemia (n = 38) Pseudobacteraemia (n = 30)
*The percentages add up to more than 100% because some patients had more than one underlying disease.
NS, not significant.
Sex
    Male 23 (61) 13 (43) NS
    Female 15 (39) 17 (57)
Mean age (SD) 64 (26.3) 70 (21.6) NS
Underlying disease*
    Gastrointestinal tract disease 11 (29) 7 (23) NS
    Hepatobiliary tract disease 11 (29) 1 (3) <0.01
    Malignancy 11 (29) 6 (20) NS
    Hypertension 11 (29) 10 (33) NS
    Diabetes mellitus 7 (18) 6 (20) NS
    Cerebrovascular accident 6 (16) 13 (43) <0.05
    Immobilisation and/or bed sore 4 (11) 16 (53) <0.005
    Chronic renal failure 3 (8) 0 (0) NS
Blood culture isolate
    C barati 0 (0) 1 (3) NS
    C difficile 1 (3) 0 (0) NS
    C disporicum 1 (3) 0 (0) NS
    C indolis 0 (0) 1 (3) NS
    C innocuum 0 (0) 1 (3) NS
    C orbiscindens 0 (0) 1 (3) NS
    C paraputrificum 1 (3) 3 (10) NS
    C perfringens 30 (79) 21 (70) NS
    C ramosum 3 (8) 0 (0) NS
    C septicum 1 (3) 0 (0) NS
    C sporosphaeroides 0 (0) 1 (3) NS
    C tertium 1 (3) 1 (3) NS
Community/hospital acquired
    Community 30 (79) 21 (70) NS
    Hospital 8 (21) 9 (30)
Number of positive blood cultures
    1 34 (89) 30 (100) NS
    2 4 (11) 0 (0)
Mono/polymicrobial bacteraemia
    Monomicrobial 19 (50) 16 (53) NS
    Polymicrobial 19 (50) 14 (47) NS

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