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J Clin Pathol 58:190-195 doi:10.1136/jcp.2004.018978
  • Original article

Ultrastructural changes in dysferlinopathy support defective membrane repair mechanism

Table 3

 Ultrastructural data

Sarcolemma and subsarcolemmal region Sarcoplasmic region
Patient Inflammation Basal lamina Microvilli pseudop Amorphous material Vesicles Myofibril lysis Central nuclei Mitochondria Lipids Stroma
–, Normal; ±, mild increase; +, moderate increase; ++, prominent increase.
BL ++ + ++ ++ ++ + + +
BR ++ ++
GP + + + +
CR ++ + + ++ ++ + +
CM ++ + + ++ ++ + + +
PB + + + ++ ++ + + +
BA + + ± +
BA + + + ± ± + +
CC ++ + +
MG + + ± +

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