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J Clin Pathol 2005;58:1325-1327 doi:10.1136/jcp.2005.026807
  • Case report

A “crackleware” oesophagus

  1. M Westerterp1,
  2. O R C Busch1,
  3. J J G H M Bergman2,
  4. F J W ten Kate3,
  5. J J B van Lanschot1
  1. 1Department of Surgery, Academic Medical Centre/University of Amsterdam, Suite G4-123, Meibergdreef 9, 1105 AZ, The Netherlands
  2. 2Department of Gastroenterology, Academic Medical Centre/University of Amsterdam
  3. 3Department of Pathology, Academic Medical Centre/University of Amsterdam
  1. Correspondence to:
    Dr M Westerterp
    Department of Surgery, Academic Medical Centre/University of Amsterdam, Suite G4-123, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands; m.westerterpAMC.UVA.NL
  • Accepted 21 March 2005

Abstract

This case report describes a 70 year old woman with excessive diffuse keratinisation of the oral cavity and oesophagus harbouring a squamous cell carcinoma. This excessive diffuse keratinisation of normally non-keratinised squamous epithelium could not be identified in normally non-keratinised epithelia in other parts of the body (the vagina), arguing against a genetic basis for this disorder. The term “crackleware” oesophagus was used to describe this entity, which has not been described previously in the English literature.

Footnotes

  • The patient gave permission for this case report to be published

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