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J Clin Pathol 58:1290-1293 doi:10.1136/jcp.2004.023259
  • Original article

Necrobiotic palisading granulomas associated with breast carcinoma

Table 1

 Details of the 4 cases reported here

Case Site Type of granuloma IHC Diagnosis
IHC, immunohistochemistry.
1 1 of 10 lymph nodes Necrobiotic Negative Necrobiotic granulomatous
2 9 of 20 lymph nodes Necrobiotic and epithelioid granulomata (1 node); necro-biotic granulomata (1 node); epithelioid granulomata adjacent to metastases (5 nodes); epithelioid granulomata without associated metastatic carcinoma (2 nodes) Positive Metastatic tumour necrosis with granulomatous inflammation
3 Stroma Necrobiotic Positive Tumour necrosis with granulomatous inflammation
4 5 of 9 lymph nodes Necrobiotic (2 nodes); epithelioid (3 nodes) Negative Necrobiotic granulomatous lymphadenitis

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