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J Clin Pathol 58:1265-1270 doi:10.1136/jcp.2004.016972
  • Original article

Characterisation of adherens and tight junctional molecules in normal animal larynx; determining a suitable model for studying molecular abnormalities in human laryngopharyngeal reflux

Table 2

 Summary of ultrastructural results

Species Laryngeal histology E-cadherin β Catenin Occludin ZO-1
E-cadherin and β catenin immunohistochemistry was scored using a semiquantitative scoring system: +, weak expression; ++, moderate expression as assessed by immunohistochemistry. (W), presence of protein as confirmed by western blot analysis.
ZO-1, zonula occludens 1.
Human Stratified squamous epithelium; respiratory-type epithelium ++ (W) ++ (W) (W) (W)
Pig Stratified squamous epithelium; respiratory-type epithelium ++ (W) ++ (W) (W) (W)
Guinea pig Stratified squamous epithelium + (W) + (W) (W) (W)
Rat Stratified squamous epithelium + (W) + (W) (W) (W)
Mouse Stratified squamous epithelium + (W) + (W) (W) (W)
Rabbit Stratified squamous epithelia; respiratory-type epithelium ++ (W) ++ (W) (W) (W)

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