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J Clin Pathol 58:1249-1254 doi:10.1136/jcp.2005.026575
  • Original article

FAT, E-cadherin, β catenin, HER 2/neu, Ki67 immunoexpression, and histological grade in intrahepatic cholangiocarcinoma

Table 3

 Kappa statistic (p value) of Ki67, HER 2/neu, E-cadherin, β catenin, FAT, and histological grade in 31 intrahepatic cholangiocarcinomas

Ki67 HER 2/neu M-E-cadherin M-β catenin N-β catenin FAT
Results in bold are significant.
H grade, high histological grade; Ki67, high Ki67 index (>10%); HER 2/neu, strong membranous staining of HER 2/neu; M-E-cadherin, reduced membranous staining of E-cadherin; M-β catenin, reduced membranous staining of β catenin; N-β catenin, positive nuclear staining of β catenin; FAT, reduced immunoexpression of FAT.
H grade −0.03 (0.58) 0.33 (<0.01) −0.21 (0.89) −0.11 (0.73) 0.15 (0.06) 0.22 (0.11)
Ki67 0.1318 (0.0696) −0.09 (0.73) 0.19 (0.08) 0.05 (0.17) 0.34 (0.02)
HER 2/neu −0.13 (0.81) 0.02 (0.44) 0.41 (<0.01) 0.10 (0.65)
M-E-cadherin 0.40 (0.01) −0.12 (0.86) −0.07 (0.65)
M-β catenin 0.24 (0.02) 0.45 (<0.01)
N-β catenin 0.15 (0.06)

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