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J Clin Pathol 58:1194-1198 doi:10.1136/jcp.2005.026765
  • Original article

Interobserver reproducibility of histological features in cutaneous malignant melanoma

Table 5

 Kappa values for the 13 parameters evaluated in 64 malignant melanomas, comparing the performance of each pathologist for each parameter with the majority diagnosis

Feature Mean
*Calculated in 55 invasive lesions.
Dimension >6 mm 1.00
Asymmetry 0.95
Poor circumscription 0.92
Irregular and confluent nests 0.96
Single melanocytes predominating 0.91
Absence of maturation* 0.93
Suprabasal melanocytes 0.87
Asymmetrical melanin 0.87
Melanin in deep cells* 0.93
Cytological atypia 0.85
Mitoses* 0.94
Necrosis* 1.00
Dermal lymphocytic infiltrate 0.70

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