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J Clin Pathol 58:1135-1142 doi:10.1136/jcp.2005.027185
  • Original article

Pathology parameters and adjuvant tamoxifen response in a randomised premenopausal breast cancer trial

Table 6

 Univariate analyses of RFS and BCS in patients without adjuvant tamoxifen treatment

Variable RFS BCS
RR 95% CI p Value RR 95% CI p Value
BCS, breast cancer survival; CI, confidence interval; IDC, invasive ductal carcinomas; ILC, invasive lobular carcinoma; NHG, Nottingham histological grade; RFS, recurrence free survival; RR, relative risk.
Tumour type ILC v IDC 0.63 0.32 to 1.24 0.17 0.71 0.34 to 1.46 0.35
Ki-67 3 v 1+2 1.58 1.06 to 2.35 0.03 1.90 1.24 to 2.92 0.003
Mitotic index 2+3 v 1 1.98 1.34 to 2.92 0.01 2.06 1.32 to 3.19 0.001
NHG 3 v 1+2 1.82 1.30 to 2.54 <0.001 2.42 1.67 to 3.53 <0.001
Age Continuous 0.97 0.94 to 0.99 0.009 0.96 0.93 to 0.99 0.006
Node status N+ v N0 1.97 1.29 to 3.02 <0.01 2.21 1.35 to 3.61 <0.01
Tumour size T2 v T1 1.24 0.89 to 1.73 0.21 1.40 0.96 to 2.03 0.08

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