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J Clin Pathol 58:1096-1100 doi:10.1136/jcp.2004.025072
  • Original article

A shift to a peripheral Th2-type cytokine pattern during the carcinogenesis of cervical cancer becomes manifest in CIN III lesions

Table 2

 Plasma concentrations of IL-4 and IL-10 in HR-HPV positive patients with cervical dysplasia and in HR-HPV negative and positive controls

Group N IL-4 > detection limit* in x/N plasmas IL-10 > detection limit* in x/N plasmas
*Detection limit for IL-4, 2 pg/ml; detection limit for IL-10, 1 pg/ml.
CIN, cervical intraepithelial neoplasia; HPV, human papillomavirus; HR, high risk; IL, interleukin.
HR-HPV− controls 11 2/11 2/11
HR-HPV+ controls 10 1/10 0/10
HR-HPV+ CIN II 10 2/10 0/10
HR-HPV+ CIN III 11 1/11 4/11
HR-HPV+ carcinoma 12 3/12 7/12

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