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J Clin Pathol 58:1086-1090 doi:10.1136/jcp.2004.021576
  • Original article

IHC for Her2 with CBE356 antibody is a more accurate predictor of Her2 gene amplification by FISH than HercepTest™ in breast carcinoma

Table 2

 Comparison of CBE356 and HercepTest IHC positive cases according to sensitivity, specificity, accuracy and predictive values

CBE356 2+/3+ HT 2+/3+
HT, HercepTest; IHC, immunohistochemistry; NPV, negative predictive value; PPV, positive predictive value.
Sensitivity 89% 66%
Specificity 95% 98%
PPV 84% 92%
NPV 97% 91%
Accuracy 94% 91%

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