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J Clin Pathol 58:1081-1085 doi:10.1136/jcp.2005.025817
  • Original article

Melanoma inhibitor of apoptosis protein is expressed differentially in melanoma and melanocytic naevus, but similarly in primary and metastatic melanomas

Table 3

 Method comparison for ML-IAP detection in melanoma

N Negative (%) Positive (%)
IHC, immunohistochemistry; ISH: in situ hybridisation; ML-IAP, melanoma inhibitor of apoptosis protein; RT-PCR, reverse transcription polymerase chain reaction.
IHC versus ISH, p = 0.5937; IHC versus RT-PCR, p = 0.1523; ISH versus RT-PCR, p = 0.2625.
IHC 34 10 (29.4) 24 (70.6)
ISH 28 10 (35.7) 18 (64.3)
RT-PCR 21 11 (52.4) 10 (47.6)

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