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J Clin Pathol 58:7-14 doi:10.1136/jcp.2003.014159
  • BEST PRACTICE NO 180
  • Review

Best Practice No 180 Nephrectomy for renal tumour; dissection guide and dataset

Table 1

 Fuhrman nuclear grading of renal carcinoma49

Grade Features
Grade 1 Round uniform nuclei approximately 10 μm in diameter with very small or absent nucleoli
Grade 2 Slightly irregular nuclear contours and diameters of approximately 15 μm with nucleoli visible at ×400
Grade 3 Moderately to severely irregular nuclear contours and diameters of approximately 20 μm, with large nucleoli visible at ×100
Grade 4 Nuclei similar to grade 3 but also multilobular, multiple, or bizarre nuclei and heavy clumps of chromatin

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