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J Clin Pathol 58:61-68 doi:10.1136/jcp.2004.020552
  • Original article

Distribution of HPV infection and tumour markers in cervical intraepithelial neoplasia from cone biopsies of Mozambican women

Table 5

 Percentage of Ki-67 and p53 positive cells according to the presence or absence of HPV and the different HPV types/combinations and CIN lesions in all sections from the five cases

Ki-67 p53
Values are mean (SD).
*Three HPV positive sections (1 with HPV-35 and 2 with HPV-33 and HPV-35) could not be used for Ki-67 and p53 evaluation because of a lack of material.
CIN, cervical intraepithelial neoplasia; HPV, human papillomavirus.
HPV negative (n = 16) 23.9 (23.6) 6.5 (12.4)
HPV positive (n = 36) * 25.9 (13.7) 3.1 (5.0)
HPV-33/58 (n = 14) 26.1 (10.7) 4.9 (5.2)
HPV-33/35 (n = 14) 23.0 (16.2) 0.8 (1.5)
HPV-16/33/35 (n = 2) 29.0 (1.4) 0
HPV-16 (n = 2) 35.5 (27.6) 10.0 (14.1)
HPV-58 (n = 1) 24 3
Normal (n = 2) 0.5 (0.7) 0.5 (0.7)
CIN I (n = 20) 19.3 (13.7) 1.5 (2.7)
CIN III (n = 27) 31.6 (17.4) 6.5 (10.4)

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