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J Clin Pathol 57:861-866 doi:10.1136/jcp.2003.015487
  • Original article

Aberrant epithelial expression of trefoil family factor 2 and mucin 6 in Helicobacter pylori infected gastric antrum, incisura, and body and its association with antralisation

Table 1

 Expression of trefoil family factor 2 (TFF2) and MUC6 in Helicobacter pylori positive and negative patients at different gastric sites in relation to the mucosal types

Percentage of cases with positive TFF2/MUC6 staining
Antrum Incisura Body
N Foveola Gland N Foveola Gland N Foveola Gland
*p<0.001, compared with H pylori negative cases; †p<0.001, compared among antral type, transitional type, and body type, χ2 test, df = 2.
df, degrees of freedom; NA, not available.
H pylori negative 49 4.1/4.1 100/100 49 2.0/0 22.4/22.4 49 4.1/2.0 2.0/2.0
    Antral type 45 4.4/4.4 100/100 8 0/0 75.0†/75.0† 0 NA NA
    Transitional type 4 0 100/100 28 3.6/0 17.9/17.9 3 0/0 0/0
    Body type 0 NA NA 13 0/0 0/0 46 4.3/2.2 2.2/2.2
H pylori positive 27 59.3*/63.0* 100/100 27 44.4*/48.1* 85.2*/85.2* 27 14.8/14.8 14.8/11.1
    Antral type 27 59.3/63.0 100/100 20 55.0/60.0 100†/100† 1 100/100 100/100
    Transitional type 0 NA NA 6 16.7/16.7 50.0/50.0 3 33.3/33.3 66.7/66.7
    Body type 0 NA NA 1 0/0 0/0 23 8.7/8.7 4.3/0

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