Table 3
The immunohistochemical evaluation of the asymptomatic postmenopausal endometria
| Parameter | A/I | A/WP | p Value* | Non-neoplastic | p Value† |
|---|---|---|---|---|---|
| Values are mean, SD, median, range. | |||||
| *Note similarities in EFGR, MIB1, and MVD reactivity between cancer tissues and weakly proliferative glands; †p values are given in comparison with atrophic/inactive endometrium. | |||||
| A/I, atrophic and inactive; A/WP, atrophic and weak proliferative activity; EGFR, endothelial growth factor receptor; ER, oestrogen receptor; MVD, microvessel density; PR, progesterone receptor. | |||||
| ER epithelium | 85, 22, 90, 20–100 | 77, 28, 80, 10–100 | 0.48 | 75, 31, 80, 10–90 | 0.56 |
| ER stroma | 50, 40, 65, 0–90 | 39, 30, 0, 0–90 | 0.18 | 41, 20, 0, 0–90 | 0.25 |
| PR epithelium | 60, 33, 60, 0–100 | 76, 19, 80, 40–100 | 0.22 | 78, 19, 80, 40–100 | 0.26 |
| PR stroma | 23, 32, 20, 0–90 | 29, 31, 5, 0–50 | 0.62 | 28, 21, 5, 0–50 | 0.69 |
| EGFR | 16, 20, 5, 0–50 | 77, 17, 80, 30–90 | <0.0001 | 55, 17, 60, 20–90 | 0.001 |
| MIB1 | 1, 5, 3, 0, 0–10 | 11, 5, 10, 2–20 | <0.0001 | 9, 5, 5, 2–15 | <0.0001 |
| MVD | 14, 8, 10, 4–33 | 23, 7, 24, 12–36 | 0.006 | 27, 6, 26, 14–42 | 0.001 |
