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J Clin Pathol 57:822-828 doi:10.1136/jcp.2004.017087
  • Original article

Topographical localisation of cagA positive and cagA negative Helicobacter pylori strains in the gastric mucosa; an in situ hybridisation study

Table 1

 Correlation between genotyping for cagA by PCR in isolated single colonies and by in situ hybridisation in biopsy sections from the stomach

Patient Disease Site PCR cagA* In situ hybridisation
cagA(+) cagA(−)
*Results of PCR test for cagA to single colonies isolates; 7 to 10 colonies were isolated from each biopsy site.
DU, duodenal ulcer; GU, gastric ulcer; ND, not determined; NUD, non-ulcer dyspepsia; PCR, polymerase chain reaction.
249 DU Antrum + +
Corpus + ND ND
Fundus + +
Incisura + +
251 DU Antrum +
Corpus +
Fundus +
Incisura +
252 GU Antrum + +
Corpus +
Fundus +
Incisura +
254 NUD Antrum +
Corpus +
Fundus +
Incisura +
256 DU Antrum + +
Corpus + +
Fundus + +
Incisura + +
259 DU Antrum + + +
Corpus +/− + +
Fundus +/− + +
Incisura +/− + +
261 GU Antrum + +
Corpus + +
Fundus + +
Incisura + ND ND

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