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J Clin Pathol 57:773-775 doi:10.1136/jcp.2003.015743
  • Short report

Are heterogenous results of EGFR immunoreactivity in renal cell carcinoma related to non-standardised criteria for staining evaluation?

Table 1

 Membranous and/or cytoplasmic EGFR immunoreactivity and intensity of membranous staining in RCC, in addition to the relation between strong membranous EGFR immunostaining and pT category and tumour grade

Conventional RCCs (n = 132)
N %
EGFR, epidermal growth factor receptor; RCC, renal cell carcinoma.
Overall immunoreactivity
    Negative 9 7
    + 2 2
    ++ 11 8
    +++ 110 83
Membranous staining
    Score 0 10 8
    Score 1+ 18 14
    Score 2+ 24 18
    Score 3+ 80 61
Stage
    pT1a 24/45 53
    pT1b 15/21 71
    pT2 2/5 40
    pT3a 16/27 59
    pT3b 23/34 68
Grade
    G1 5/16 31
    G2 41/68 60
    G3 31/44 70
    G4 3/4 75

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