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J Clin Pathol 57:598-603 doi:10.1136/jcp.2003.013177
  • Original article

Tissue invasiveness and non-acidic pH in human candidiasis correlate with “in vivo” expression by Candida albicans of the carbohydrate epitope recognised by new monoclonal antibody 1H4

Table 2

Tissue distribution of 1H4 immunoreactivy of Candida albicans in human superficial and systemic candidiasis

Tissue No of cases 1H4 immunoreactivity
Epithelial surface Invasive
Yeast Hyphae Yeast Hyphae
1H4 immunoreactivity: −, negative; +/−, <50% positive cells; +, >50% positive cells; empty spaces, fungal elements were not present in this form or location.
CNS, central nervous system.
Skin 3 + +
Tongue 2 + + +
Oesophagus 4 + + +
Stomach 4 + +/− +
Intestine 2 + +/− +
Urethra 1 +/− + + +
Kidney 2
    Glomeruli + +
    Tubules + +
    Collecting ducts +
Bronchus 1 + + +
Lung 2 + +
Myocardium 1 + +
Thyroid 1 + +
CNS 1 + +

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