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J Clin Pathol 57:591-597 doi:10.1136/jcp.2003.013508
  • Original article

Prognostic impact of VEGF, CD31, CD34, and CD105 expression and tumour vessel invasion after radical surgery for IB–IIA non-small cell lung cancer

Table 8

Studies correlating neoangiogenesis and survival in NSCLC

First author Year Number of patients Stage Factor Correlation
NS, not significant; NSCLC, non-small cell lung cancer; S, significant; VEGF, vascular endothelial growth factor.
Giatromanolaki6 1997 134 I, II CD31 NS
Pastorino8 1997 137 I CD31 NS
Fontanini9 1997 407 I–III CD34 S
Duarte26 1998 106 I VIII, CD31 S, NS
Imoto27 1998 91 I–III VEGF S
Matsuyama11 1998 101 I–III CD34 S
Decaussin12 1999 81 I, II VEGF NS
Kakolyris13 1999 69 I, II CD31 S
Yano5 2000 108 I–IV CD34, VEGF S, NS
Koukourakis10 2001 102 I, II VEGF S
Han14 2001 85 I VEGF S
Offersen7 2001 143 I–III VEGF, CD34 NS, NS
Tanaka15 2001 236 I–III CD105, CD34 S, NS

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