Table 1
Number of sections positive for PAR-2 staining (% of positive sections with two independent antibodies) in relation to the stage of the atherosclerotic lesions
| Stage of lesion | ||||
|---|---|---|---|---|
| Class I | Class II | Class III | Class IV | |
| We examined 72 class I and class II atherosclerotic lesions, 49 from arterial serial sections of 8 adults and 23 from arterial serial sections of 6 elderly men. Moreover, we studied 96 class III and class IV atherosclerotic lesions, 43 from arterial serial sections of 8 adults and 53 from arterial serial sections of 6 elderly men. *p<0.01 v class I and II lesions; †p<0.01 v class II lesions; ‡p<0.05 v class I lesions. | ||||
| PAR-2, protease activated receptor 2. | ||||
| PAR-2 (B2 antibody) | 56% (8%) | 69% (11%) | 43% (12%) | 25% (9%)* |
| PAR-2 (SAM11 antibody) | 43% (10%) | 58% (14%) | 46% (14%) | 28% (11%)†‡ |
