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J Clin Pathol 57:449-455 doi:10.1136/jcp.2003.008656
  • Review

HPV infections and tonsillar carcinoma

Table 2

Detection of HPV in normal tonsillar mucosa or benign lesions

Type of lesion Technique No of cases 6/11 16 18 31 33 First author (date)
In total, 17/200 (8.5%) samples were HPV positive.
HPV, human papillomavirus; ISH, in situ hybridisation; PCR, polymerase chain reaction; SB, Southern blotting.
Tonsillitis SB 0/20 Brandsma (1989)33
Chronic inflammatory disease ISH 0/30 Niedobitek (1990)29
Tonsillitis PCR 0/7 Snijders (1992)5
Normal posterior tonsillar pilar PCR, SB 1/3 1 Smith (1993)60
Chronic tonsillitis PCR, SB 4/28 4 Watanabe (1993)38
Adenoid hyperplasia and chronic tonsillitis PCR, SB 0/8, 5/38 5 Fukushima (1994)61
Condyloma SB 1/1 1 Tominaga (1996)62
Normal mucosa SB 3/3 3 Tominaga (1996)62
Chronic tonsillitis PCR 0/14 Klussmann (2001)50
Tonsillar hyperplasia PCR, SB 3/48 3 Strome (2002)51

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