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J Clin Pathol 57:360-364 doi:10.1136/jcp.2003.012369
  • Original article

Unfavourable prognosis of patients with trisomy 18q21 detected by fluorescence in situ hybridisation in t(11;18) negative, surgically resected, gastrointestinal B cell lymphomas

Table 1

Clinical and molecular cytogenetic data of patients with t(11;18) negative gastrointestinal B cell lymphoma

Patient Age Sex Location Subtype Stage Treatment Recurrence (month) FU Result Chrom 18 aberration
FU, follow up (in months); chrom, chromosome; m, male; f, female; low, low grade marginal zone lymphoma of MALT type; DLBCL+l., diffuse large B cell lymphoma with coexistent low grade marginal zone lymphoma of mucosa associated lymphoid tissue type; DLBCL, diffuse large B cell lymphoma; GE, gastrectomy; CT, chemotherapy; HCE, hemicolectomy; RT, radiotherapy; ER, eradication of Helicobacter pylori; IR, intestinal resection; DWD, dead with disease; DWOD, dead without disease; AWD, alive with disease; AWOD, alive without disease; +18, complete trisomy of chromosome 18; +18q, partial trisomy of chromosome 18; +18/+18q*, mosaic pattern with 33% +18 and 40% +18q.
1 80 m Stomach Low EI 1 GE 219 DWOD
2 41 f Stomach Low EI 1 GE 115 AWOD
3 81 m Stomach Low EI 1 GE 39 AWOD
4 61 m Stomach Low EI 2 GE+CT 8 DWOD
5 49 m Large bowel Low EII 1 HCE+CT+RT Locally (22) 22 DWD +18q
6 66 f Stomach Low EII 1 GE 52 DWOD
7 66 f Stomach Low EII 1 GE+CT 55 AWOD +18
8 66 m Stomach Low EII 1 GE+CT+ER 60 AWOD
9 79 m Stomach Low EIV GE+CT+ER Locally (10) 12 DWD
10 70 m Small bowel Low EIV IR+CT 5 DWD
11 51 m Stomach DLBCL+l. EI GE 96 AWOD
12 70 f Stomach DLBCL+l. EII 1 GE+CT 177 AWOD +18
13 62 m Stomach DLBCL+l. EII 1 GE 12 DWOD
14 71 f Stomach DLBCL+l. EII 1 GE+CT 57 AWOD
15 70 f Large bowel DLBCL EI 2 HCE 160 DWOD
16 50 f Stomach DLBCL EI 2 GE+RT 290 DWOD
17 70 m Stomach DLBCL EI 2 GE 1 DWD
18 79 f Stomach DLBCL EI 2 GE+CT Brain (48) 78 AWD
19 62 f Stomach DLBCL EI 2 GE 76 AWOD
20 74 m Stomach DLBCL EI 2 GE+CT 75 AWOD +18
21 76 f Stomach DLBCL EI 2 GE+CT+RT Locally (72) 109 AWOD
22 68 m Stomach DLBCL EII 1 GE+CT 80 AWOD
23 82 m Stomach DLBCL EII 1 GE 1 DWD +18/+18q*
24 71 f Stomach DLBCL EII 1 GE+CT Locally (6) 6 DWD +18q
25 68 m Stomach DLBCL EII 1 GE+CT Locally (10) 58 DWD
26 68 m Stomach DLBCL EII 1 GE+CT 80 AWOD
27 73 f Stomach DLBCL EII 1 GE+CT 24 DWOD
28 76 m Stomach+bowel DLBCL EII 1 GE+IR+CT Locally (11) 24 DWD +18q
29 64 m Stomach DLBCL EII 1 GE+CT 24 DWOD

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