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J Clin Pathol 2004;57:120
  • Echoes

New insights into early molecular events in colon cancer

For the first time, distinct gene expression profiles have been demonstrated in patients with colonic adenomas with low grade dysplasia. The detailed molecular analysis was made possible by laser mediated microdissection (LMM) of colonic crypts of normal and adenomotous colonic cryosections. This was followed by RNA arbitrarily …

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