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J Clin Pathol 57:1312-1318 doi:10.1136/jcp.2004.017954
  • Original article

nm23-H1 expression and loss of heterozygosity in colon adenocarcinoma

Table 3

 Clinicopathological features of 73 informative patients with colorectal cancer stratified by nm23-H1 LOH status

Characteristic nm23-H1 LOH
Negative (%) (n = 53) Positive (%) (n = 20) p Value
LOH, loss of heterozygosity.
Age
    <70 years 28 (70.0) 12 (30.0)
    ⩾70 years 22 (73.3) 8 (26.7) 0.79
Sex
    Male 20 (62.5) 12 (37.5)
    Female 33 (80.5) 8 (19.5) 0.11
Tumour size
    ⩽5 cm 31 (73.8) 11 (26.2)
    >5 cm 11 (64.7) 6 (35.3) 0.53
Histological grade (differentiation)
    Well 12 (80.0) 3 (20.0)
    Moderate 13 (72.2) 5 (27.8)
    Poor 7 (50.0) 7 (50.0) 0.24
Dukes’s stage
    A 12 (80.0) 3 (20.0)
    B 12 (75.0) 4 (25.0)
    C 25 (67.6) 12 (32.4) 0.72

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