Table 2
Expression of ATM, p53, and MRN complex proteins in myoepithelial tumours
| Case | Diagnosis | ATM score | p53 | p63 | CK5/6 | ER | αSMA |
|---|---|---|---|---|---|---|---|
| +, focally positive; ++, diffusely positive; αSMA, α smooth muscle actin; ER, oestrogen receptor; NA, not available. | |||||||
| 1 | Adenomyoepithelioma | 4 | Negative | + | + | NA | NA |
| 2 | Adenomyoepithelioma | 0 | Negative | NA | NA | NA | NA |
| 3 | Adenomyoepithelioma | 0 | NA | ++ | NA | ++ | ++ |
| 4 | Malignant myoepithelioma | 3 | Positive | + | + | – | + |
| 5 | Malignant myoepithelioma | 3 | Negative | ++ | ++ | NA | NA |
| 6 | Malignant myoepithelioma | 2 | Positive | ++ | ++ | – | ++ |
| 7 | Malignant myoepithelioma | 2 | Positive | ++ | ++ | – | ++ |
| 8 | Malignant myoepithelioma | 0 | Positive | ++ | ++ | – | + |
| 9 | Malignant myoepithelioma | 0 | Positive | – | NA | NA | NA |
| 10 | Malignant myoepithelioma | 0 | Negative | ++ | ++ | – | – |
| 11 | Malignant myoepithelioma | 0 | Negative | ++ | ++ | NA | NA |
| 12 | Malignant myoepithelioma | 0 | Negative | ++ | NA | NA | NA |
| 13 | Malignant myoepithelioma | 0 | NA | ++ | ++ | ++ | – |
| 14 | Matrix producing breast carcinoma | 3 | Positive | + | + | – | + |
| 15 | Sarcomatoid breast carcinoma | 0 | Positive | + | + | – | ++ |
| 16 | Sarcomatoid breast carcinoma | 0 | Negative | NA | NA | – | – |
| 17 | Sarcomatoid breast carcinoma | 12 | Positive | ++ | + | – | – |
| 18 | Sarcomatoid breast carcinoma | 0 | Negative | ++ | ++ | – | – |
