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J Clin Pathol 57:1069-1074 doi:10.1136/jcp.2004.016733
  • Original article

Expression of SRC-1, AIB1, and PEA3 in HER2 mediated endocrine resistant breast cancer; a predictive role for SRC-1

Table 2

 Recurrence rates and protein expression of ERα, ERβ, PEA3, AIB1, and SRC-1 in HER2 positive versus HER2 negative patients

Total group (70) HER2 positive (%) HER2 negative (%) p Value (Bonferroni’s adjusted p value)
Statistical analysis was performed using the Fisher’s exact test. The p values were adjusted for multiple comparisons using Bonferroni’s inequality.
ER, oestrogen receptor.
Recurrence 19 16 (46%) 3 (9%) 0.0009 (0.0054)
ERα positive 60 28 (80%) 32 (91%) 0.3059 (1.0000)
ERβ positive 37 11 (31%) 26 (74%) 0.0007 (0.0042)
PEA3 positive 36 24 (69%) 12 (34%) 0.0081 (0.0486)
AIB1 positive 40 26 (74%) 14 (40%) 0.0074 (0.0444)
SRC-1 positive 18 16 (46%) 2 (6%) 0.0002 (0.0012)

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