Clinical phenotype of haemoglobin Q-H disease
- Division of Haematology, Department of Pathology, The University of Hong Kong, Queen Mary Hospital, Hong Kong
- Correspondence to: Dr E S K Ma Division of Haematology, Department of Pathology, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong; eskmahkucc.hku.hk
- Accepted 24 June 2003
Abstract
Seven patients of Chinese origin who had haemoglobin (Hb) Q-H disease were studied. They were found to have a similar clinical phenotype to that of patients with deletional Hb H disease, who have a near identical genotypic configuration. The complete absence of Hb A in Hb Q-H disease and the similar clinical phenotype to deletional Hb H disease lends support to the observation that Hb Q-Thailand shares similar functional properties with Hb A.
